Once Human Mayfly

Once Human Mayfly: Introduction

The Mayfly faction in Once Human is where rebels, dreamers, and ex-Rosetta scientists all rolled the dice on freedom—and lived to tell the tale, mostly. Born from betrayal and forged by necessity, Mayfly exists as the thorn in Rosetta’s side and the last hope for humanity’s autonomy. They’re not the biggest group in town, but they punch well above their weight with brains, grit, and more than a few jury-rigged miracles. If you’re the kind of player who likes being the underdog with a cause, the Once Human Mayfly Guide is your launchpad.

Mayfly doesn’t have Rosetta’s factories or their shiny drones, but what they lack in numbers, they make up for in ingenuity. Their weapons and gear are often repurposed tech—less polished, more personal. Think duct tape over steel plating and software hacks that turn old tech into battlefield gold. The Once Human Mayfly Guide highlights how these scrappy innovators thrive in chaos, making them ideal for players who prefer flexibility, stealth, and outsmarting rather than overpowering their foes.

Their low population isn’t a bug—it’s a feature. Mayfly players often find tighter communities, where coordination and teamwork matter more than raw firepower. And because they’re fighting uphill most of the time, victories feel earned, not handed out. If Rosetta is the empire, Mayfly is the resistance. That’s the core spirit of the Once Human Mayfly Guide: survive, adapt, resist—and maybe blow up a Rosetta tower or two along the way.

Once Human Mayfly: Prismverse’s Clash Scenario

In the Prismverse’s Clash, Mayfly isn’t just fighting a war—they’re fighting for reality itself. Rosetta’s meddling with prism deviations threatens to tear the secondary plane apart, and Mayfly is the last line of defense. This is where the Once Human Mayfly Guide comes into its own: you’re not just another gun on the field—you’re the unpredictable variable that could shatter Rosetta’s plans. Your role isn’t just to survive the battlefield; it’s to tip the balance before everything collapses into dust and regret.

Mayfly forces may not match Rosetta in tech or drone firepower, but they make up for it with tactical aggression and a deep understanding of the terrain. They’ve turned the black plains into a chessboard of ambushes, flanks, and guerrilla tactics. The Once Human Mayfly Guide helps players master the fine art of disruption—how to deny prism deviations to Rosetta, stall their experimental progress, and sabotage their plans with well-timed strikes. Victory in this mode isn’t about brute strength—it’s about smart moves and quick thinking.

You won’t be alone either. Allies like Ron offer Mayflies interdimensional flexibility, letting you pop up where you’re least expected. And while Rosetta throws waves of tech at the problem, Mayfly counters with determination and resourcefulness. Tasks leading up to the final assault serve as prep missions, but also as character-building moments—because Mayflies don’t just win battles, they earn them. The Once Human Mayfly Guide exists to make sure every player walks into this scenario knowing they matter and that their actions have weight.

Once Human Mayfly: Content & Activities

The Once Human Mayfly Guide brings you the specifics of how to thrive in the world of Mayfly, starting with the key side missions and seasonal events. One notable activity is the Mayfly Badge Side Mission, found at Hurst Industries. To complete this mission, you’ll need to track down symbols and follow them to a weapon crate. Once you have the Mayfly badge, it’s time to head to Claire to claim your reward. The mission not only rewards you with useful items but also delves into the lore of the Mayfly faction and its connection to other characters like Marco and his sister.

The Once Human Mayfly Guide also highlights seasonal events, such as the Mayfly’s Fantastic Journey Event, which runs until September 5, 2024. This event gives you a chance to dive into nine sets of quests spanning three categories—Survival, Combat, and Territory. You’ll complete these sequentially, with the ultimate goal of defeating Arachsiam. The tasks are designed to feel like part of normal gameplay, but it’s important to ensure you’re meeting all the necessary conditions for each quest. Completing these quests will earn you unique rewards like Activators, Blueberry Sodas, and possibly even a Matrix – AWS.338.

To deepen your gameplay, Mayfly offers faction-specific memetic specializations at various levels. The Once Human Mayfly Guide provides an in-depth look at these specializations, like the Level 5 Injection Items that include Nurture Coherence Injection, enhancing resource-gathering abilities. At Level 20, you unlock powerful Gene Types like the Lightning Gene, great for combat-focused solo play. Finally, at Level 40, you can access Gene Fabrics to upgrade your armor with unique buffs, such as the Extreme Gene Fabric, which provides substantial damage reduction. Alongside these specializations, Mayfly offers cosmetics like the “fast win mayfly set,” as well as unique gear such as Mayfly Goggles, which are perfect for Shock builds.

Once Human Mayfly: Pros and Cons

Siding with the Once Human Mayfly faction in Once Human offers rapid growth, mobility, and resource efficiency, giving players an edge early on with specialized units designed for swift strikes and guerrilla tactics. However, Once Human Mayfly faction’s fragility and lack of late-game power make them vulnerable to more durable factions as the game progresses, and their reliance on speed can leave them exposed in prolonged battles.

Pros of Siding with Mayfly:

Cons of Siding with Mayfly:

Siding with the Once Human Mayfly faction offers rapid growth, mobility, and resource efficiency, giving players an edge early on with specialized units designed for swift strikes and guerrilla tactics. However, their fragility and lack of late-game power make them vulnerable to more durable factions as the game progresses, and their reliance on speed can leave them exposed in prolonged battles.

Once Human Mayfly: Gene Fragments

In the Once Human Mayfly Guide, obtaining Gene Fragments is key to crafting powerful injections, so understanding the process is crucial. To start, you’ll need to have the Gene Extractor in your backpack. Without it, you won’t have a chance to gather any fragments. Once you’re ready, defeating Deviants becomes your next task. These creatures drop different types of Gene Fragments, which you can use to create the items you need. The key here is knowing which type of Deviant to hunt based on the fragments you’re after.

There are several types of Gene Fragments, each dropped by different Deviants. Deviant Fragments are dropped by regular Deviants like Nar and Charred Maniac. Anima Fragments, on the other hand, come from Anima Deviants such as the Watcher or Agent. If you’re after Starlith, focus on Elite Deviants like Glutton, Star Walker, or Arbor. These fragments are used for high-level crafting, including the Lightning Gene and other legendary Mayfly recipes. Finally, Matterlith can be obtained from Morphic enemies, which can be found in places like the Morphic fridge, weapon crate, and armor crate.

When it comes to farming Starlith, the Once Human Mayfly Guide recommends focusing on runs through Monolith of Greed and Blackfell. These locations have a high concentration of Elite Deviants that respawn quickly, making it easier for you to gather large quantities of Starlith in a short amount of time. If you’re serious about crafting the best Mayfly materials, these spots are your go-to locations for farming.

Once Human Mayfly: Tips for Mayfly Players

In the Once Human Mayfly Guide, choosing the right faction specializations can make a huge difference in how you approach the game. If you’re playing solo, focusing on combat, the Judgment Injection should be your go-to. Follow that up with the Lightning Gene and Lightning Gene Fabric for a solid setup. These choices will enhance your ability to fight on your own, making you a powerful force in one-on-one situations. However, if you’re part of a team and focusing on territory control, the Elysium Injection paired with Extreme Gene and Extreme Gene Fabric is the better route. This setup is all about boosting your team’s territorial strength and keeping things in your favor during group encounters.

When it comes to farming Starlith, efficiency is key in the Once Human Mayfly Guide. The best strategy is to take on Elite Deviants in places like the Monolith of Greed or Blackfell. These locations are packed with powerful enemies, and using the Gene Extractor will give you the best chance to gather the precious Starlith you need. Since these Elite Deviants respawn quickly, you can make the most of your time by running through these areas repeatedly, collecting large amounts of Starlith in a short span.

During events like the Mayfly’s Fantastic Journey, preparation is everything. Make sure to review all the tasks beforehand to get a clear idea of what’s needed for optimal progress. The Once Human Mayfly Guide stresses the importance of paying attention to specifics, like the type of weapon or workbench required for each task. This way, you can avoid wasting time on tasks that don’t contribute to your overall goals and ensure you’re maximizing progress as you go about your regular gameplay. Learn how to play Once Human by checking out our Once Human Beginner Guide, packed with tips and strategies to help you master the game.

Frequently Asked Questions (FAQ)